The need for change is pervasive. Society is facing global challenges that demand immediate action. These challenges are not new. Yet, progress is slow. Why? Fundamentally, because people are creatures of habits which are hard to change. Cognitive and emotional issues interact to make known choices preferred to novel solutions. This session will present evidence that identify some of the root causes behind resistance to change. On this basis, it will propose a learning and development format to leverage recent work in neuroplasticity and innovation sciences that supports change and transformation in individuals and organisations.